Compared with O + L group, score was higher in O - L group (P < 0.05). order: accuracy; author; title; date; order: normal; reversed; items per page: 10; 20; 50; 100; Previous. Han, Dongji, Li, Shiyong, Xiong, Qiuju, Zhou, Ling, Luo, Ailin. Western blotting and quantitative PCR showed that after overexpressing miR-208, expression of E-cadherin, an epithelial cell marker, was decreased and expression of fibronectin and vimentin, interstitial cell markers, was increased in pancreatic cancer cell line BxPC3; however, after inhibiting miR-208, increased E-cadherin expression and decreased fibronectin and vimentin expression were observed in pancreatic cancer cell line BxPC3. The journal is published by Springer Science+Business Media and the editor-in-chief is Lawrence J. Berliner. The aim of this study was to investigate the effect of intermittent high glucose on the expression of IL-18, MCP-1, and PAI-1 and adiponectin in 3T3-L1 adipocytes. Cell biochemistry and biophysics Totowa, NJ : Humana Press, c1996-Online Access 1979 - latest: SpringerLink Journals - AutoHoldings. In total, 4012 patients (2205 female) with a mean age of 56.5 (23-87) years were treated. During the development of obesity, adipose tissue releases a host of different adipokines and inflammatory cytokines, such as leptin, resistin, tumor necrosis factor α (TNF-α), Interleukin-6 (IL-6), and adiponectin, which mediate insulin resistance. Elevated circulating concentrations of interleukin-18 (IL-18), monocyte chemoattractant protein-1 (MCP-1), and plasminogen activator inhibitor-1 (PAI-1) and decrease of adiponectin are associated with obesity-related diseases. 2. It appeared that in comparison to younger patients the elderly population is likely to be more susceptible to vertigo. In situ hybridization studies showed that miR-21 was primarily localized and distributed in cortical glomerular and renal tubular cells in diabetic kk-ay kidney. Our results showed that miR-335 is significantly upregulated with treatment of leptin, resistin, TNF-α, and IL-6 in human mature adipocytes, and its expression elevated in the process of adipocyte differentiation. Percutaneous glycerol injection into Meckel's cavity is widely used to treat trigeminal neuralgia. No serious adverse effects were observed. A family history of malignant tumors in first-degree relatives was documented in 48.3 % of the husbands and 48.7 % of the wives. Furthermore, reduction of FAK or ERK1/2 phosphorylation by FAK small interfering RNA (FAK siRNA) potentiated the effect of alpha-mangostin. I: Calcium Modulation at pH 7.20, instructions how to enable JavaScript in your web browser, Journal / Magazine / Newspaper, Internet Resource. Ischemic postconditioning (IPO) reduces lethal reperfusion injury under normal conditions, but its effectiveness in hypercholesterolemia (HC) is disputed. Effect of Propofol on the Expression of MMP-9 and Its Relevant Inflammatory Factors in Brain of Rat with Intracerebral Hemorrhage. microRNA-199a (miR-199a) is a highly conserved miRNA, always deregulated in numerous human tumors. Get this from a library! Furthermore, western blot analysis disclosed that miR-29b could abolish Smad3 activation. 1. 2. … In this article, the improved roles of FDG as an in-vivo glycolytic marker which reflect biological changes across in-vitro cellular environment are discussed. The objective of this study is to assess the clinical role of computed tomography angiography (CTA) in determining the etiology of aneurysmal subarachnoid hemorrhage (ASAH) and selecting the treatment options. This was associated with gallbladder stones in 37 patients (94.9 %), choledocholith in 11 patients (28.2 %), and Mirizzi syndrome in 5 patients (12.8 %). The expression and secretion of IL-18, MCP-1, PAI-1, and adiponectin were determined by real-time RT-PCR and ELISA, respectively.The production of reactive oxygen species (ROS) and 8-hydroxydeoxyguanosine(8-OHdG) were measured. However, there are no data in the literature assessing how this system operates in human umbilical arteries (HUA). The MSCs were used as seed cells and transplanted into an apatite-wollastonite magnetic bioactive glass-ceramic (AW MGC) vector to construct artificial tissue-engineering scaffolds that were then implanted into the in vivo rabbit radial bone defect model. Some reports demonstrated that α-tomatine had various anti-carcinogenic properties. Best of BJ 2020 … Further, genotypic/allelic frequencies and clinical characteristics were compared between two groups. However, protein extraction experiments indicated that densin exhibited a significant hydrophobic interaction with the cell membrane that was not expected of cytosolic proteins. Morphological changes associated with apoptosis were observed by electron microscopy and Hoechst staining. Western blot results showed the expression of BRP-39, and TGF-β1 had the same trend in different groups. Cell Biochemistry and Biophysics | Citations: 2,433 | Read 1100 articles with impact on ResearchGate, the professional network for scientists. DLCO; n = 28). This study was to determine whether miR-21 was involved in diabetic nephropathy and to explore the relationship between miR-21 and MMP9/TIMP1 expression in diabetic nephropathy. The Publication History of Cell Biochemistry and Biophysics covers 1979-1985, 1989-1990, 1995-ongoing. Thus, at physiological pH for the HbS, the Ca-SDS interaction increases the tendency for protein denaturation in comparison to the HbA. TSG-pretreatment also inhibited ICAM-1/VCAM-1 expression in Ox-LDL-induced U937 cells. Jia-Jun Liu, Xue-Jun Dai, Yan Xu, Pei-Qing Liu, Yong Zhang, Xiao-Dan Liu, Zhi-Gang Fang, Dong-Jun Lin, Ruo-Zhi Xiao, Ren-Wei Huang, He-Qing Huang. Psoriasis, a common inflammatory skin disease, is characterized by epidermal hyperplasia, abnormal differentiation, angiogenesis, immune activation, and inflammation. customise view. Effect of Propofol on the Expression of MMP-9 and Its Relevant Inflammatory Factors in Brain of Rat with Intracerebral Hemorrhage. The intermittent glucose was more effective in triggering the generation of ROS than stable high glucose. Año: 2015. However, no significant differences in the +1858C>T genotypic (CC, CT) and allelic (C, T) frequencies were found. Cell Biochemistry and Biophysics (CBB) aims to publish papers on the nature of the biochemical and biophysical mechanisms underlying the structure, control and function of cellular systemsThe reports should be within the framework of modern biochemistry and chemistry, biophysics and cell physiology, physics and engineering… Interestingly, miR-21 expression positively correlated with urine albumin creatine ratio (ACR), TIMP1, collagen IV (ColIV), and fibronectin (FN); while negatively correlated with creatine clearance ratio (Ccr) and MMP-9 protein. ISSN 1085-9195; Visibility; Title: CELL BIOCHEMISTRY AND BIOPHYSICS related ISSN: 1559-0283 Country: United States. However, due to the heterogeneity in the meta-analysis, the results should be interpreted with caution. The protein tyrosine phosphatase non-receptor 22 (PTPN22) gene encodes for lymphoid protein tyrosine phosphatase. Detailed understanding of these processes is necessary for the progress of … Nanodiscs in Membrane Biochemistry and Biophysics Chem Rev. Intraoperative observations showed that all the patients had gallbladder wall thickening. On the other hand, IGFBP-3-202A/C gene polymorphism did not seem to be associated with all the cancer sites in any genetic model and ethnicity. The Novel Heterocyclic Trioxirane [(1,3,5-Tris Oxiran-2-yl)Methyl)-1,3,5-Triazinane-2,4,6-Trione (TATT)] Exhibits a Better Anticancer Effect than Platinum-Based Chemotherapy by Induction of Apoptosis and Curcumin Further Enhances its Chemosensitivity, Effects of HA-1077 and Y-27632, Two Rho-Kinase Inhibitors, in the Human Umbilical Artery, The-1123G > C Variant of PTPN22 Gene Promoter is Associated with Latent Autoimmune Diabetes in Adult Chinese Hans, Iodine-125 Seed Implantation in the Treatment of Sacrococcygeal Chordoma: A Case Report, Application of 128 Slice 4D CT Whole Liver Perfusion Imaging in Hepatic Tumor, α-Mangostin Suppresses Phorbol 12-myristate 13-acetate-induced MMP-2/MMP-9 Expressions via αvβ3 Integrin/FAK/ERK and NF-κB Signaling Pathway in Human Lung Adenocarcinoma A549 Cells, Suppression of 12-O-Tetradecanoylphorbol-13-Acetate-Induced MCF-7 Breast Adenocarcinoma Cells Invasion/Migration by α-Tomatine Through Activating PKCα/ERK/NF-κB-Dependent MMP-2/MMP-9 Expressions, Effect of Low-Intensity Pulsed Ultrasound on MMP-13 and MAPKs Signaling Pathway in Rabbit Knee Osteoarthritis, Association of the SNP rs1800925(C/T) in the Interleukin-13 Gene Promoter with Pulmonary Function in Chinese Han Patients with Idiopathic Pulmonary Fibrosis, Matrix Metalloproteinase-14 Expression and Its Prognostic Value in Cervical Carcinoma, mir-143 and It’s Emerging Role as a Modulator of Systemic Carcinogenesis, 18[F]FDG-PET/CT is a Useful Molecular Marker in Evaluating Tumour Aggressiveness: A Revised Understanding of an In-Vivo FDG-PET Imaging that Alludes the Alteration of Cancer Biology, Intermittent High Glucose Stimulate MCP-l, IL-18, and PAI-1, but Inhibit Adiponectin Expression and Secretion in Adipocytes Dependent of ROS, Densin-180 is Not a Transmembrane Protein, A Clinical Epidemiological Study in 187 Patients with Vertigo, IGF1(CA)19 and IGFBP-3-202A/C gene polymorphism and cancer risk: a meta-analysis, Lentivirus-Mediated Overexpression of MicroRNA-199a Inhibits Cell Proliferation of Human Hepatocellular Carcinoma, Effects of miR-19b Overexpression on Proliferation, Differentiation, Apoptosis and Wnt/β-Catenin Signaling Pathway in P19 Cell Model of Cardiac Differentiation In Vitro, Triple Point-Mutants of Hypoxia-Inducible Factor-1α Accelerate In Vivo Angiogenesis in Bone Defect Regions, Analysis of the relationship between ultrasound of breast cancer DOT-SDI and the expression of MVD, VEGF and HIF-1α, 2,3,4′,5-Tetrahydroxystilbene-2-O-β-D-glucoside Suppresses Expression of Adhesion Molecules in Aortic Wall of Dietary Atherosclerotic Rats and Promonocytic U937 Cells, Total Glucosides of Peony Attenuates 2,4,6-Trinitrobenzene Sulfonic Acid/Ethanol-Induced Colitis in Rats Through Adjustment of Th1/Th2 Cytokines Polarization, An EP4 Antagonist ONO-AE3-208 Suppresses Cell Invasion, Migration, and Metastasis of Prostate Cancer, miR-208-Induced Epithelial to Mesenchymal Transition of Pancreatic Cancer Cells Promotes Cell Metastasis and Invasion, Effect of miR-21 on Renal Fibrosis by Regulating MMP-9 and TIMP1 in kk-ay Diabetic Nephropathy Mice. We have provided immunofluorescence evidence showing that none of the tested epitope sites in densin was accessible to extracellularly applied antibodies. The total number of lung cancer and commonly seen female-specific cancers (breast, ovarian, uterine, and cervical) was 127 (55.2 %). Cell Biochemistry and Biophysics > 2000 > 32 > 1-3 > 213-220. Also, there was one patient who was misdiagnosed in the CTA. In our study, we found MiR-429 was down-regulated in primary osteosarcoma lesion and osteosarcoma cell lines. Lung cancer ranked first for the females. As a result, a fragment about 600-bp length upstream sequences of miR-335 had apparent transcription activity. 1. For the in vitro experiment, rabbit bone marrow mesenchymal stem cells (MSCs) were divided into four experimental groups. Cell Biochemistry and Biophysics Volume 62; Issue 1. Cell Biochem Biophys. Further investigation confirmed that miR-199a significantly reduced the endogenous protein level of HIF-1α in hypoxia. ISSN / EISSN : 0163-4992 / 1559-0283 Current Publisher: Springer Science and Business Media LLC (10.1007) Former Publisher: Springer Science and Business Media LLC (10.1385) Total articles ≅ 2,626. The expressions of MMP-14 in normal cervical mucosa and cervical carcinoma tissue were detected with immunohistochemistry. Postconditioning protocol induced six cycles of 10s ischemia and 10s reperfusion at the onset of the reperfusion. First, the result demonstrated α-tomatine could inhibit TPA-induced the abilities of the adhesion, morphology/actin cytoskeleton arrangement, invasion, and migration by cell-matrix adhesion assay, immunofluorescence stain assay, Boyden chamber invasion assay, and wound-healing assay. In conclusion, the rs1800925 T allele of the IL-13 gene is associated with worse pulmonary function in patients with IPF of Chinese Han ethnicity. The IL-13 CC genotype was present in 28/70 (40.0 %), homozygous TT in 6/70 (8.6 %) and heterozygous CT in 36/70 (51.4 %) patients with IPF. The current study shows that MMP-14 may be an independent prognostic factor for cervical carcinoma patients. These findings indicated a novel role for miR-335 in adipose tissue inflammation, and miR-335 might play an important role in the process of obesity complications via its own transcription mechanism. View all articles. Authors ZiQi Tao 1 , Aimin Shi 2 , Cuntao Lu 3 , Tao Song 4 , Zhengguo Zhang 5 , Jing Zhao 6 Affiliations 1 Department of Science … 1. For this purpose, 60 male Sprague-Dawley rats were randomly-and-equally divided into six groups. MicroRNAs (miRs) play important roles in initiation and progression of many pathologic processes. Cell Biochemistry and Biophysics is a laboratory-oriented journal devoted to illuminating the biophysical mechanisms controlling cell functions. File: PDF, 730 KB. Osteosarcoma is the most common primary bone tumor. Overexpression of miR-19b inhibited activation of the Wnt/β-catenin signaling pathway in P19 cells, which may regulate cardiomyocyte differentiation. Compared with controls, type-II collagen expression was less in O + L/O - L groups, with more significant decrease in O - L group (P < 0.05). In oncology, this approach can be directly applied as translational biomarkers of disease progression. Volume 62, issue 3, April 2012. In the current study, matured human adipocytes were treated with TNF-α, IL-6, leptin, or resistin on the 15th day after the induction of human pre-adipocyte differentiation. Finally, this review will point out that mechanical properties are a critical determinant for the efficiency of cancer cell invasion and the progression of cancer which might affect the future development of new cancer treatments. Extracellular domains of the transmembrane glycoprotein, neuropilin-1 (Np1), specifically bind an array of factors and co-receptors including class-3 semaphorins (Sema3a), vascular endothelial growth factor (VEGF), hepatocyte growth factor, platelet-derived growth factor BB, transforming growth factor-β 1 (TGF-β1), and fibroblast growth factor2 (FGF2). In psoriatic lesional skin, involucrin was detected in the stratum spinosum, but not in the basal or the cornified layer. Thus, significant differences in the distribution of alleles at -1112 region of IL-13 gene were observed among the study groups A, B, and C, with the highest frequency in group C (p < 0.05). Clinical manifestation of the disease was similar to general cholecystitis and preoperative CT examination showed that there were only 4 XGC cases, while the others were possibly misdiagnosed. Effect of Propofol on the Expression of MMP-9 and Its Relevant Inflammatory Factors in Brain of Rat with Intracerebral Hemorrhage. Overview Cell Biochemistry and Function publishes original research articles and reviews on the mechanisms whereby molecular and biochemical processes control cellular activity with a particular emphasis on the integration of molecular and cell biology, biochemistry and physiology in the regulation of tissue function in health and disease. We previously reported that over-expression of EP4 was one of the mechanisms responsible for progression to castration-resistant prostate cancer, and an EP4 antagonist ONO-AE3-208 in vivo suppressed the castration-resistant progression regulating the activation of androgen receptor. After overexpressing miR-208, p-AKT and p-GSK-3β expression was altered by activating AKT/GSK-3β/snail signaling pathway. However, the presence of Ca appeared to diminish the adverse effects of the SDS on HbA. Cell Biochemistry and Biophysics' journal/conference profile on Publons, with 634 reviews by 243 reviewers - working with reviewers, publishers, institutions, and funding agencies to turn peer review into a measurable research output. We conclude that kidney transplantation has no significant impact on the growth, development, health, and intelligence of the offspring born to recipients. Triple point-mutations (in amino acids 402, 564, and 803) in the HIF1α coding sequence (CDS) were induced by polymerase chain reaction. Research Areas Include: • Enzyme and protein structure, … Recent data indicated miRNAs may be involved in the pathogenesis of osteosarcoma, suggesting some novel targets for therapy. Initial structural analyses suggest that densin is a transmembrane protein and may participate in cell-adhesion function between pre- and post-synaptic membranes. From December 1983 to November 2008, patients with primary trigeminal neuralgia were treated in our clinic using percutaneous glycerol injection into Meckel's cavity which was conducted according to the Hakanson's anterior puncture method with some modifications. These meditations occur mostly over a beer, as the subject is old, almost classical, dating back to the emergence of the term biophysics in Pearson´s musing, in 1892, where it replaced etiology, emphasizing the primacy of physics laws over capricious and complex living matter. The difference in age at diagnosis between spouses was less than 10 years in 134 couples (58.3 %), while 77 (33.5 %) couples had an age difference less than 5 years. Cell Biochemistry and Biophysics. Accumulating studies have evaluated the association of Alpha-2-Macroglobulin gene (A2M) 5 bp insertion/deletion (5 bp I/D, rs3832852) and Ile1000Val (rs669) polymorphisms with Alzheimer's disease (AD) risk, but the results remain inconclusive. The results of microarray analysis indicated that miR-199a was frequently downregulated in hepatocellular carcinoma (HCC). Importantly, antagomir-21 not only ameliorated Ccr and ACR but also decreased TIMP1, ColIV, and FN proteins. Cell Biochemistry and Biophysics is published by Humana Press, Inc., which is located in the United States. The animals from each group were killed 8 weeks after the surgery, and the tissues from the implantation region were harvested for the evaluation of the angiogenesis. Emphasis is placed on the relationship between molecular structure and the nature of the specific property/function under investigation. However, preincubation of HUA with HA-1077 or Y-27632 (10(-5) M for both) did not affect the 5-HT-induced contractions in this medium. Overview of Calpain-Mediated R The aim of this study was to analyze the association of EP4 with prostate cancer metastasis and the efficacy of ONO-AE3-208 for suppressing the metastasis. miR-208 mimic, miR-208 inhibitor and NC were transfected into pancreatic cancer cell line Bxpc3 using liposome. The adding of the NAC, aspecific pharmacological inhibitor of ROS, normalized the expression of these adipokines and the levels of ROS and 8-OHdG under both stable and intermittent glucose conditions.Intermittent high glucose induces a greater aberrant production of key adipokines than stable high glucose, and this effect seems to be related to over-production of ROS. Compared to parental cells or cells transfected with a control vector, the overexpression of microRNA-199a in the HCC cell lines HepG2 stably was showed to reduce cell proliferation in vitro and in vivo.
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